| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022552 | Neurobiology of Disease | 2012 | 10 Pages |
Abstract
⺠High-fat diet impacts metabolic determinants and induces insulin resistance. ⺠High-fat diet renders dopaminergic terminals more vulnerable to MPTP degeneration. ⺠High-fat intake could represent of modifiable risk factor of Parkinson's disease.
Keywords
TNFHFDGDNFDOPACDATDTAMPTPGFAPMIPMCPDocosatetraenoic acidGM-CSFDPA1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine3,4-dihydroxyphenylacetic acidBDNFSNpcArachidonic aciddocosapentaenoic aciddocosahexaenoic acidLinoleic acidDopamine transporterinterferonIFNinterleukinParkinson's diseaseNutritionsubstantia nigra pars compactatyrosine hydroxylaseARADopamineDHAhigh-fat dietcontrol dietCytokinesGranulocyte macrophage colony stimulating factorGlial cell line-derived neurotrophic factorBrain-derived neurotrophic factortumor necrosis factorFlow cytometryLeukocytesObesityInsulin resistanceDopaminergic neuronsmonocyte chemotactic proteinGlial fibrillary acidic proteinmacrophage inflammatory protein
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Authors
M. Bousquet, I. St-Amour, M. Vandal, P. Julien, F. Cicchetti, F. Calon,