| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022556 | Neurobiology of Disease | 2012 | 9 Pages |
Abstract
⺠Reducing miR-181a protects the brain from stroke and neural cells from ischemic stress. ⺠miR-181 increases in the core but decreases in the penumbra after MCAO. ⺠Reciprocal expression of miR-181a and GRP78 protein was found. ⺠GRP78, an essential ER protein, is a target of miR-181. ⺠miR-181 causes translational arrest of GRP78 mRNA after ischemia.
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Authors
Yi-Bing Ouyang, Yu Lu, Sibiao Yue, Li-Jun Xu, Xiao-Xing Xiong, Robin E. White, Xiaoyun Sun, Rona G. Giffard,