| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022582 | Neurobiology of Disease | 2012 | 10 Pages |
Abstract
⺠A model of isolated interictal spiking in the rat neocortex was characterized. ⺠Interictal spiking develops gradually and spreads to larger cortical areas. ⺠Interictal spiking leads to layer specific gene and pathway activation that can be blocked with a MAPK inhibitor. ⺠Interictal spiking produces hyperactive behaviors.
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Authors
Daniel T. Barkmeier, Danielle Senador, Karine Leclercq, Darshan Pai, Jing Hua, Nash N. Boutros, Rafal M. Kaminski, Jeffrey A. Loeb,