| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022595 | Neurobiology of Disease | 2012 | 12 Pages |
Abstract
⺠Bone marrow mononuclear (BMC) cells were transplanted to epileptic rats. ⺠Marked reduction in frequency and duration of seizures were observed. ⺠Treatment with BMCs decreased neuronal loss and/or induced an endogenous neurogenesis. ⺠BMCs transplantation downregulated the expression of pro-inflammatory cytokines mRNA. ⺠BMCs transplantation upregulated the expression of IL-10 in the brain.
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Authors
Zaquer S.M. Costa-Ferro, Bruno S.F. Souza, Marcos M.T. Leal, Carla Martins Kaneto, Carine Machado Azevedo, Igor Campos da Silva, Milena B.P. Soares, Ricardo Ribeiro-dos-Santos, Jaderson C. DaCosta,