| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022606 | Neurobiology of Disease | 2012 | 9 Pages |
Abstract
⺠JNK signaling is activated in retinal ganglion cell axons soon after axonal injury. ⺠Specific JNK isoforms, JNK2 and JNK3, are activated in the axon. ⺠Inhibition of JNK2 and 3 significantly delays death after axonal injury. ⺠JUN is the downstream effector of JNK activation.
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Authors
Kimberly A. Fernandes, Jeffrey M. Harder, Laura B. Fornarola, Robert S. Freeman, Abbot F. Clark, Iok-Hou Pang, Simon W.M. John, Richard T. Libby,