Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022630 | Neurobiology of Disease | 2012 | 7 Pages |
Abstract
⺠One Hz stimulation of the subiculum inhibits both kindling and kindled seizures. ⺠This antiepileptic effect shows wider time-window than stimulating other targets. ⺠This treatment abolishes pilocarpine-induced spontaneous seizures. ⺠This treatment does not show time-dependent property in pilocarpine model. ⺠This antiepileptic effect shows frequency-dependent characteristic.
Keywords
ADTDBSLFSGSTGSDHFSTLEafterdischargegeneralized seizure thresholdADDElectroencephalogramstatus epilepticusafterdischarge thresholdEpilepsylow-frequency stimulationdeep brain stimulationhigh-frequency stimulationanalysis of varianceANOVAGeneralized seizureSubiculumtemporal lobe epilepsyafterdischarge durationEEG
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Authors
Kai Zhong, Deng-Chang Wu, Miao-Miao Jin, Zheng-Hao Xu, Yi Wang, Wei-Wei Hou, Xiao-Ming Li, Shi-Hong Zhang, Zhong Chen,