| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022635 | Neurobiology of Disease | 2012 | 8 Pages |
Abstract
⺠Infarct volumes and behavioral deficits were reduced in FP antagonist AL8810 mice. ⺠Similar results in FP knockout mice after permanent ischemic stroke. ⺠FP receptor blockade protects against oxygen glucose deprivation cell death in organotypic slices. ⺠Neuronal death is less in cells treated with AL8810 not in cultured astrocytes. ⺠FP receptor agonist increases intracellular calcium levels of cultured neurons.
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Authors
Yun Tai Kim, Sang Kwan Moon, Takayuki Maruyama, Shuh Narumiya, Sylvain Doré,