Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022637 | Neurobiology of Disease | 2012 | 13 Pages |
Abstract
⺠Subtle abnormalities in motor skills were found in a DYT1 knock-in model of dystonia with multiple motor tasks. ⺠Striatal microdialysis showed reduced baseline and amphetamine-stimulated dopamine release. ⺠Anatomical studies revealed a small reduction in TH-immunopositive nigrostriatal neurons, with a small increase in soma size.
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Authors
Chang-Hyun Song, Xueliang Fan, Cicely J. Exeter, Ellen J. Hess, H.A. Jinnah,