Article ID Journal Published Year Pages File Type
6022637 Neurobiology of Disease 2012 13 Pages PDF
Abstract
► Subtle abnormalities in motor skills were found in a DYT1 knock-in model of dystonia with multiple motor tasks. ► Striatal microdialysis showed reduced baseline and amphetamine-stimulated dopamine release. ► Anatomical studies revealed a small reduction in TH-immunopositive nigrostriatal neurons, with a small increase in soma size.
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