| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022660 | Neurobiology of Disease | 2012 | 10 Pages |
Abstract
⺠Retinal phenotype in mouse model of Huntington's disease. ⺠Retinal change appeared by 13 weeks of age, co-incident with motor dysfunction. ⺠A functional cone deficit likely arose from loss of cone opsin and transducin protein. ⺠Ectopic rod photoreceptors and remodelled rod and cone bipolar cells were observed. ⺠There was an increase in Müller cell gliosis, yet limited cell loss.
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Authors
Abrez Hussain Batcha, Una Greferath, Andrew I. Jobling, Kirstan A. Vessey, Michelle M. Ward, Jess Nithianantharajah, Anthony J. Hannan, Michael Kalloniatis, Erica L. Fletcher,