| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022696 | Neurobiology of Disease | 2012 | 9 Pages |
Abstract
âºThe role of mitochondrial oxidative stress in epilepsy was investigated. âºMice deficient in mitochondrial antioxidant (Sod2â/â) showed spontaneous electrographic and motor seizures. âºSeizures, oxidative stress and bioenergetic parameters in Sod2â/â mice were attenuated by a catalytic antioxidant. âºMitochondrial oxidative stress is a contributing mechanism to epilepsy in Sod2-/- mice.
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Authors
Li-Ping Liang, Simon Waldbaum, Shane Rowley, Ting-Ting Huang, Brian J. Day, Manisha Patel,