Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022716 | Neurobiology of Disease | 2011 | 5 Pages |
Abstract
⺠Misfolded proteins are cleared by the ubiquitin proteasomal system and autophagy. ⺠Aging reduces the function of the ubiquitin proteasomal system. ⺠Aging increases the accumulation of Huntington disease proteins and promotes neuropathology.
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Authors
Xiao-Jiang Li, Shihua Li,