Article ID Journal Published Year Pages File Type
6022742 Neurobiology of Disease 2011 13 Pages PDF
Abstract
► Mutant tau leads to Alzheimer's disease cellular pathologies in Aplysia neurons. ► Pathological changes are prevented by incubation of neurons in 10 nM paclitaxel. ► 100 nM paclitaxel does not ameliorate the pathological changes, and facilitate them. ► Paclitaxel can prevent the pathology but not reverse it once it started.
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