Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022742 | Neurobiology of Disease | 2011 | 13 Pages |
Abstract
⺠Mutant tau leads to Alzheimer's disease cellular pathologies in Aplysia neurons. ⺠Pathological changes are prevented by incubation of neurons in 10 nM paclitaxel. ⺠100 nM paclitaxel does not ameliorate the pathological changes, and facilitate them. ⺠Paclitaxel can prevent the pathology but not reverse it once it started.
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Authors
Or A. Shemesh, Micha E. Spira,