Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022762 | Neurobiology of Disease | 2011 | 9 Pages |
Abstract
⺠Brains of aging YAC128 mice show features consistent with human Huntington disease. ⺠Regions of specific sparing as well as atrophy are observed in aging YAC128 mice. ⺠Classification trees identify regions that discriminate YAC128 from wild type mice. ⺠Progressive cortical pathology in the YAC128 mice restricted to projection layers.
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Authors
Jeffrey B. Carroll, Jason P. Lerch, Sonia Franciosi, Amanda Spreeuw, Nagat Bissada, R. Mark Henkelman, Michael R. Hayden,