Article ID Journal Published Year Pages File Type
6022782 Neurobiology of Disease 2012 9 Pages PDF
Abstract
► Seizures in vitro are preceded by an interneuron-dominated pre‐ictal burst. ► Interneuron-pyramidal cell firing is tightly coupled following the pre‐ictal burst. ► Chloride transiently increases during seizure, raising EGABA above spike threshold. ► Blocking GABAA receptors results in short bursting, small chloride transients.
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Life Sciences Neuroscience Neurology
Authors
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