Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022782 | Neurobiology of Disease | 2012 | 9 Pages |
Abstract
⺠Seizures in vitro are preceded by an interneuron-dominated preâictal burst. ⺠Interneuron-pyramidal cell firing is tightly coupled following the preâictal burst. ⺠Chloride transiently increases during seizure, raising EGABA above spike threshold. ⺠Blocking GABAA receptors results in short bursting, small chloride transients.
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Authors
Kyle P. Lillis, Mark A. Kramer, Jerome Mertz, Kevin J. Staley, John A. White,