Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022799 | Neurobiology of Disease | 2010 | 15 Pages |
Abstract
⺠LRRK2 transgenic mice have reduced extracellular dopamine levels in the striatum. ⺠LRRK2 G2019S transgenic mice show alterations in tau processing. ⺠LRRK2 G2019S mice display anxiety like behavior.
Keywords
DABDOPACDATHWT3,3′-diaminobenzidine tetrahydrochloride3,4-dihydroxyphenylacetic acidBACAnxietyDopamine transporterParkinson's diseaseanalysis of varianceANOVATransgenictyrosine hydroxylaseDopaminemicrodialysisneuropathologyhomovanillic acidpolymerase chain reactionPCRHVAhigh performance liquid chromatographyHPLCbacterial artificial chromosomeleucine rich repeat kinase 2
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Authors
H.L. Melrose, J.C. Dächsel, B. Behrouz, S.J. Lincoln, M. Yue, K.M. Hinkle, C.B. Kent, E. Korvatska, J.P. Taylor, L. Witten, Y.-Q. Liang, J.E. Beevers, M. Boules, B.N. Dugger, V.A. Serna, A. Gaukhman, X. Yu, M. Castanedes-Casey, M.J. Farrer,