Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022819 | Neurobiology of Disease | 2010 | 11 Pages |
Abstract
âºExcitotoxicity mediated by GluA4-containing Ca-AMPARs involves the JNK pathway. âºActivation of the JNK pathway downstream of Ca-AMPARs is Ca2+-dependent. âºIn the rat hippocampus the GluA4 subunit may interact with the JNK scaffold JIP-1. âºThe interaction with GluA4 occurs through the N-terminal domain of JIP-1.
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Authors
M. Vieira, J. Fernandes, A. Burgeiro, G.M. Thomas, R.L. Huganir, C.B. Duarte, A.L. Carvalho, A.E. Santos,