Article ID Journal Published Year Pages File Type
6022819 Neurobiology of Disease 2010 11 Pages PDF
Abstract
►Excitotoxicity mediated by GluA4-containing Ca-AMPARs involves the JNK pathway. ►Activation of the JNK pathway downstream of Ca-AMPARs is Ca2+-dependent. ►In the rat hippocampus the GluA4 subunit may interact with the JNK scaffold JIP-1. ►The interaction with GluA4 occurs through the N-terminal domain of JIP-1.
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Authors
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