Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022828 | Neurobiology of Disease | 2011 | 10 Pages |
Abstract
âºComplement immunoreactivity is significantly higher in ALS than control tissue. âºMore activated microglia are found in slow than rapid progressing ALS patients. âºInflux of adaptive immune cells is observed in ALS spinal cord and motor cortex âºMore dendritic cells are found in rapid than slow progressing ALS patients. âºBased on our findings we propose a positive feedback loop driven by C1q.
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Authors
M. Sta, R.M.R. Sylva-Steenland, M. Casula, J.M.B.V. de Jong, D. Troost, E. Aronica, F. Baas,