Article ID Journal Published Year Pages File Type
6022828 Neurobiology of Disease 2011 10 Pages PDF
Abstract
►Complement immunoreactivity is significantly higher in ALS than control tissue. ►More activated microglia are found in slow than rapid progressing ALS patients. ►Influx of adaptive immune cells is observed in ALS spinal cord and motor cortex ►More dendritic cells are found in rapid than slow progressing ALS patients. ►Based on our findings we propose a positive feedback loop driven by C1q.
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Life Sciences Neuroscience Neurology
Authors
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