Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022833 | Neurobiology of Disease | 2011 | 11 Pages |
Abstract
âºIncreased Ca2+ in mitochondria, ER and cytoplasm preceded SOD1G93A inclusions. âºIncreased cytosolic Ca2+ promoted SOD1G93A inclusion formation. âºProteasome inhibition caused mitochondrial abnormalities, but independent of Ca2+. âºGeldanamycin prevented inclusions and mitochondrial rounding, but not altered Ca2+.
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Authors
Miranda L. Tradewell, Laura A. Cooper, Sandra Minotti, Heather D. Durham,