Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022838 | Neurobiology of Disease | 2011 | 8 Pages |
Abstract
⺠OGD elicited cytotoxicity in hippocampal slices is not CD36 dependent. ⺠Microglia activation induced injury in hippocampal slices is also not CD36 dependent. ⺠Tissue damage by activated bone marrow-derived macrophages (BMM) is CD36 dependent. ⺠CD36 gene knockout dampens superoxide production in activated BMM. ⺠Reduction in peroxynitrite formation in CD36â/â BMM leads to neuroprotection.
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Authors
Ping Zhou, Liping Qian, Eduardo F. Gallo, Ruba S. Deeb, Josef Anrather, Steven S. Gross, Costantino Iadecola,