| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022864 | Neurobiology of Disease | 2011 | 8 Pages |
Abstract
⺠In HD, abnormalities in sleep-wake cycles deleteriously affect quality of life. ⺠Abnormalities may occur because the wake-promoting orexin system is defective. ⺠Surprisingly, we find that key components of the HD orexin circuitry are normal. ⺠Nevertheless, the day-night rhythm of orexin network activity is abnormal.
Keywords
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Rhîannan H. Williams, A. Jennifer Morton, Denis Burdakov,