Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022882 | Neurobiology of Disease | 2011 | 6 Pages |
Abstract
⺠Loss of CB1R expression worsens motor performance and increases striatal aggregates in HD mice. ⺠Loss of CB1R expression worsens motor performance and increases striatal lesions induced by 3NP intoxication. ⺠Results support that early loss of CB1 receptors seen in HD is involved in the pathophysiological development of this disorder.
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Authors
Stéphane Mievis, David Blum, Catherine Ledent,