| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022899 | Neurobiology of Disease | 2011 | 7 Pages |
Abstract
⺠50% of Parkinson's patients show weight abnormalities ⺠The serotonergic system is known to regulate appetite ⺠We studied in 34 PD patients BMI changes and serotonergic function in vivo with PET ⺠Abnormal BMI changes were linked to raised SERT function in raphe nuclei and its limbic and cognitive connections ⺠Serotonergic agents could help alleviate abnormal changes in BMI in PD
Keywords
ROIMMSEBPNDFOVMRCTACUPDRSVDRPCCPFCDASBACCH&YDopamine agonistsMRIstandard deviationParkinson's diseaseMagnetic resonance imagingPositron emission tomographyLEDSERTSerotoninserotonin transporterbody mass indexBMIMedical Research Councilprefrontal cortexposterior cingulate cortexanterior cingulate cortexMini-Mental State ExaminationUnified Parkinson's Disease Rating ScaleRegions Of InterestField of viewUnited KingdomParkinson's disease/ParkinsonismPET
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Authors
Marios Politis, Clare Loane, Kit Wu, David J. Brooks, Paola Piccini,