Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022900 | Neurobiology of Disease | 2011 | 9 Pages |
Abstract
⺠In 6 h culture, IL-4 reduced the death of microglial cells induced by staurosporine. ⺠In contrast, in long term treatment IL-4 increased the apoptotic death. ⺠IL-4 increased the levels of cleaved caspase 3 and PARP. ⺠IL-4 down regulated the autophagy and Bcl-xL in microglial cells.
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Authors
Javier A. Soria, Daniela S. Arroyo, Emilia A. Gaviglio, Maria C. Rodriguez-Galan, Ji Ming Wang, Pablo Iribarren,