Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022909 | Neurobiology of Disease | 2011 | 9 Pages |
Abstract
⺠TRPV1 channels are involved in a variety of inflammatory conditions. ⺠Genetic deletion of TRPV1 channels affected the clinical course of EAE. ⺠Ablation of TRPV1 channels exacerbated the effects of TNF-α on glutamate synapses. ⺠On the contrary, ablation of TRPV1 channels attenuated the synaptic action of IL-1β.
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Authors
Gabriele Musumeci, Giorgio Grasselli, Silvia Rossi, Valentina De Chiara, Alessandra Musella, Caterina Motta, Valeria Studer, Giorgio Bernardi, Nabila Haji, Helena Sepman, Diego Fresegna, Mauro Maccarrone, Georgia Mandolesi, Diego Centonze,