Article ID Journal Published Year Pages File Type
6022912 Neurobiology of Disease 2011 8 Pages PDF
Abstract
► Mammalian Atg8 homologues containing LC3 and GABARAPs are involved in autophagosomal formation. ► We examined whether Atg8 homologues were altered in Lewy body disease. ► All Atg8 homologues were localized in Lewy bodies. ► LC3 was the most vulnerable protein among them. ► Autophagic function can be impaired through alteration of Atg8 homologues in Lewy body disease.
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