Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022915 | Neurobiology of Disease | 2011 | 9 Pages |
Abstract
⺠Protein carbonylation occurred in rat hippocampus during excitotoxin-induced seizures. ⺠Protein damage was detected 3 h after kainate injection with cellular changes. ⺠Proteomic analysis highlighted several consistently carbonylated proteins. ⺠Molecular chaperones are targets of carbonylation. ⺠Proteins maintaining cellular/mitochondrial structure are another group of targets.
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Authors
Ayako Furukawa, Yoshiyuki Kawamoto, Yoichi Chiba, Shiro Takei, Sanae Hasegawa-Ishii, Noriko Kawamura, Keisuke Yoshikawa, Masanori Hosokawa, Shinji Oikawa, Masashi Kato, Atsuyoshi Shimada,