Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
602302 | Colloids and Surfaces B: Biointerfaces | 2008 | 7 Pages |
Abstract
The cysteamine (CA) was bound onto surface of the pretreated glassy carbon electrode (GC) with cyclic voltammetry (CV). Gold nanoparticles were self-assembled to the electrode binding with cysteamine via strong AuS covalent bond to fabricate the nano-Au self-assembled modified electrode (nano-Au/CA/GC). The modified electrode was characterized with cyclic voltammetric and ac impedance methods. The electrochemical behavior of dopamine (DA) on the modified electrode was investigated with cyclic voltammetry and differential pulse voltammetry (DPV). A well-defined redox peaks of DA on the nano-Au/CA/GC electrode were obtained at Epa = 0.175 V and Epc = 0.146 V (vs. SCE), respectively. The peak current of DA is linear with the concentration of DA in the range of 1.0 Ã 10â8 mol Lâ1 to 2.5 Ã 10â5 mol Lâ1, with the correlation coefficient of 0.998. The detection limit is 4.0 Ã 10â9 mol Lâ1 (S/N = 3). The modified electrode exhibited an excellent reproducibility, sensibility and stability for determination of DA in the presence of high concentration AA, and can be applied to determinate dopamine injection, with satisfied result.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Guang-Zhi Hu, Da-Peng Zhang, Wei-Li Wu, Zhou-Sheng Yang,