Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
602405 | Colloids and Surfaces B: Biointerfaces | 2008 | 5 Pages |
Abstract
2-(Pyridinyldithio)ethylcarbamoyl dextran (PDEC dextran) is developed herein as a novel biosensor coating material aimed for direct and facile fabrication of a sulfhydryl-specific capture surface on gold; the site-directed immobilization of a single free cysteine residue presented protein (human serum albumin, HSA) on PDEC dextran-coated surfaces without prior activation and subsequent specific binding of mouse monoclonal anti-HSA antibody to the resultant surface were demonstrated using surface plasmon resonance (SPR) assays.
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Authors
Xin Li, Christopher Abell, Matthew A. Cooper,