Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6025002 | NeuroImage | 2015 | 10 Pages |
Abstract
Targeted PAS applied to the human pharyngeal motor cortex induces local and remote changes in both primary and non-primary areas for water and saliva tasks. There is a possibility that changes of the inhibitory neurotransmitter, GABA, may play a role in the changes in BOLD signal. These findings provide evidence for the mechanisms underlying the beneficial effects of PAS on the brain swallowing network.
Keywords
HLSVDACCFOVPESNaArTMSMRSTMSN-acetylaspartatepharyngeal electrical stimulationHRFNMDAEOIMPMmotor thresholdγ-aminobutyric acidChoSwallowingHemodynamic response functionRepetitive transcranial magnetic stimulationTranscranial magnetic stimulationPaired associative stimulationanalysis of varianceANOVASMARepetition timemagnetic resonance spectroscopyOccPharynxCortexOccipital cortexMotor cortexField of viewSMA, supplementary motor areaPASNeuroplasticitycreatineCholineGABAN-methyl-d-aspartate receptor
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Authors
Emilia Michou, Steve Williams, Rishma Vidyasagar, Darragh Downey, Satish Mistry, Richard A.E. Edden, Shaheen Hamdy,