Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6028141 | NeuroImage | 2013 | 12 Pages |
Abstract
We found a robust relationship between gF and DT-MRI measures of FA, RD and MD in all major WM tracts. Higher gF score was related to higher degree of WM integrity, in middle-aged as well as old individuals. Thus, the distributed relationship between gF and indices of WM microstructure is consistent with the notion that gF reflects efficient signaling between cortical areas. Furthermore, analysis of relationships between WM measures and gF components revealed an association with information processing speed and reasoning ability, but not with episodic memory. Thus, although all subcomponents loaded high on gF factor, the speed-related components were most strongly associated with DT-MRI-derived measures. These results suggest that DT-MRI can be used to parse gF.
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Authors
Judit Haász, Erling T. Westlye, Sveinung Fjær, Thomas Espeseth, Arvid Lundervold, Astri J. Lundervold,