Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging

► Neuronatomical imaging was used to evaluate a mouse model of autism (BTBR T + tf/J) ► Significant alterations in volume were seen throughout BTBR T + tf/J brains ► Significant correlations between brain volume and behavioral variables were found ► Diffusion values were altered in white matter structures of BTBR T + tf/J mice.