Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6030136 | NeuroImage | 2013 | 8 Pages |
Abstract
⺠Significant COMTval158met Ã Drug Use interaction in prefrontal white matter was found. ⺠Reduced prefrontal FA was found only in Met allele homozygotes who are also drug users. ⺠Elevated prefrontal dopamine and drug may interact to alter white matter structure. ⺠Relevance to known prefrontal cortical deficits in addiction is discussed.
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Authors
Xiaochu Zhang, Mary R. Lee, Betty Jo Salmeron, Dan J. Stein, L. Elliot Hong, Xiujuan Geng, Thomas J. Ross, Nan Li, Colin Hodgkinson, Pei-Hong Shen, Yihong Yang, David Goldman, Elliot A. Stein,