Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6030137 | NeuroImage | 2013 | 8 Pages |
Abstract
⺠We examined human [11C]Ro15 4513 PET binding in nicotine addiction. ⺠Higher limbic GABAA availability in volunteers with a history of cigarette smoking. ⺠Higher limbic GABAA receptor availability continues with abstinence. ⺠Suggests that limbic GABAA receptor system is dysregulated in nicotine addiction. ⺠Higher GABAA receptor availability may be a trait marker for nicotine addiction.
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Authors
Paul R.A. Stokes, Aaf Benecke, Jim Myers, David Erritzoe, Ben J. Watson, Nicola Kalk, Daniela Riano Barros, Alexander Hammers, David J. Nutt, Anne R. Lingford-Hughes,