Human cortical connectome reconstruction from diffusion weighted MRI: The effect of tractography algorithm

► The tractography algorithm affects the topology of structural networks. ► Increased network density through retaining longer tracts underlies some effects. ► However, topology can change independent of network density. ► Small-worldness, efficiency and hubs are robust properties but their strength changes. ► We propose a connectome dissection QC approach using TSDC to guide algorithm choice.