| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6030752 | NeuroImage | 2012 | 8 Pages |
Abstract
⺠Estimation of relationship between AZD9272 plasma concentration and occupancy. ⺠Simultaneous estimation of radioligand kinetics and drug occupancy. ⺠Simultaneous inclusion of data from two CNS regions and all PET measurements. ⺠Shown how nonlinear mixed effects modeling can be used to integrate PET data. ⺠Less need for simplifications and approximations in the analysis.
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Authors
Matts KÃ¥gedal, Zsolt Cselényi, Svante Nyberg, Siv Jönsson, Patrick Raboisson, Per Stenkrona, Andrew C. Hooker, Mats O. Karlsson,