Calibrating the BOLD signal during a motor task using an extended fusion model incorporating DOT, BOLD and ASL data

► Using BOLD and ASL data along with DOT improves HbO2 reconstruction. ► DOT, BOLD and ASL fusion model enables estimating M value and HbT0 without a need for hypercapnia. ► We obtained an average HbT0 of 71 μM and an average M value of 0.18.