| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6030975 | NeuroImage | 2013 | 7 Pages |
Abstract
⺠Acute alcohol reduces glucose metabolism and increases acetate uptake in human brain. ⺠Enhanced brain acetate uptake with alcohol was highest in heavy alcohol users. ⺠Alcohol produced opposite changes in regional brain metabolism than acetate uptake. ⺠Results consistent with the use of acetate as brain energy source during intoxication. ⺠Heavy alcohol exposure may facilitate use of acetate as an energy substrate in brain.
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Authors
Nora D. Volkow, Sung Won Kim, Gene-Jack Wang, David Alexoff, Jean Logan, Lisa Muench, Colleen Shea, Frank Telang, Joanna S. Fowler, Christopher Wong, Helene Benveniste, Dardo Tomasi,