Quantitative MRI in the very preterm brain: Assessing tissue organization and myelination using magnetization transfer, diffusion tensor and T1 imaging

► Quantitative MRI is sensitive to multiple independent aspects of brain maturation. ► Group-wise image registration is used to create multiple averaged parametric maps. ► Various quantitative MRI measures show distinct pattern of regional variations. ► MTR values show a marked change in the pattern of regional variation with time. ► DTI parameters preserve the same order of regional values over the neonatal period.