| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6031440 | NeuroImage | 2012 | 21 Pages |
Abstract
⺠MRS provides biomarkers for translational and preclinical neuroscience research. ⺠MRS is an important tool for evidence based diagnosis and therapy monitoring. ⺠MRS can be further extended to spectroscopic imaging with μL spatial resolution. ⺠We review the role of MRS in the translation from basic to clinical neuroscience.
Keywords
outer volume suppressionCSIMRSGPCSNRBOLDNMDAN-methyl-d-aspartateGSHTCAN-acetylaspartateSCA1NaANAAGCRLBglycerylphosphorylcholine3NPOVSPChoSARnuclear magnetic resonance3-nitropropionic acidVOIGlxN-acetylaspartylglutamateγ-Aminobutyrateamyotrophic lateral sclerosistricarboxylic acidFunctional MRIMRIAlzheimer's diseaseALSHuntington's diseaseParkinson's diseaseAFPNMRChemical shift imagingMagnetic resonance imagingfMRIPositron emission tomographyvolume of interestCNSecho timeRepetition timeBBBcentral nervous systemmagnetic resonance spectroscopyNMR spectroscopyAHPRadiofrequencyPhosphorylcholinePhosphorylethanolamineblood-brain-barrierBrainspecific absorption rateSignal-to-noise ratiospinocerebellar ataxia type 1PETCramer-Rao Lower boundGABAGlutathione
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Authors
João M.N. Duarte, Hongxia Lei, VladimÃr Mlynárik, Rolf Gruetter,