Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6032037 | NeuroImage | 2012 | 7 Pages |
Abstract
⺠A high prevalence of fixation artifacts are observed in fixed mouse brain MR images. ⺠Two artifacts from perfusion fixation are described and their causes identified. ⺠Hyperintense rim around brain occurs when using powder perfusates and high flow rate. ⺠Inverse contrast and cerebellar deformation occurs upon inadequate fixation. ⺠These artifacts are unacceptable for quantitative data analysis and must be avoided.
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Authors
Lindsay S. Cahill, Christine L. Laliberté, Jacob Ellegood, Shoshana Spring, Jacqueline A. Gleave, Matthijs C. van Eede, Jason P. Lerch, R. Mark Henkelman,