Maturation of task-induced brain activation and long range functional connectivity in adolescence revealed by multivariate pattern classification

► Multivariate pattern analysis discriminates fMRI maps of 13, 17 and 21 year-olds. ► Age-affected voxels are distributed throughout the brain. ► Age-distinctive activation patterns generalize across different cognitive tasks. ► Long range functional connectivity increases from 13 to 17 and 21 years of age. ► There is no direct relationship between maturation of connectivity and activation.