| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6032369 | NeuroImage | 2012 | 8 Pages |
Abstract
⺠FTIR imaging can be used to examine individual neuron bodies in situ. ⺠Unstained, unfixed tissues are characterized by their FTIR spectrochemical signatures. ⺠We demonstrate label-free FTIR imaging of subcellular organization. ⺠Dense core amyloid plaques are infiltrated with lipid, in a mouse model of AD. ⺠Natural spectrobiochemical signatures reveal composition of neuron layers in retina.
Keywords
methylene groupCH2AβAPPSRCFpAFocal plane arrayAlzheimerdocosahexaenoic acidPolyunsaturated fatty acidsPUFAsaturated fatty acidscornu ammonisamyloid betaAlzheimer diseaseFTIR imagingCNSDHAcentral nervous systemRetinadentate gyrusFTIRFourier transform infrared spectroscopyBrainNeuronAmyloid protein precursor
Related Topics
Life Sciences
Neuroscience
Cognitive Neuroscience
Authors
M.Z. Kastyak-Ibrahim, M.J. Nasse, M. Rak, C. Hirschmugl, M.R. Del Bigio, B.C. Albensi, K.M. Gough,