| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6032945 | NeuroImage | 2011 | 10 Pages |
Abstract
⺠MRI based detection of Alzheimer's disease plaques is critically needed. ⺠Our UPSPIO-Aβ1-42 target plaques in vivo and are non-toxic. ⺠Plaque targeting is confirmed by histology. ⺠Both T2* and VBM analysis confirm the specificity of our findings. ⺠This method has the potential for clinical use with further refinement.
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Authors
Jing Yang, Youssef Zaim Wadghiri, Dung Minh Hoang, Wai Tsui, Yanjie Sun, Erika Chung, Yongsheng Li, Andrew Wang, Mony de Leon, Thomas Wisniewski,