| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6033069 | NeuroImage | 2012 | 9 Pages |
Abstract
⺠We performed 5-HT phMRI in chronic fluoxetine-treated juvenile and adult rats. ⺠Juvenile treatment caused an opposite phMRI response compared to adult treatment. ⺠An age by treatment interaction effect was seen in 5-HT related brain regions. ⺠Our findings probably reflect neuronal imprinting effects of early SSRI treatment. ⺠phMRI is suitable to non-invasively assess age-related differences in 5-HT response.
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Authors
A. Klomp, J.L. Tremoleda, M. Wylezinska, A.J. Nederveen, M. Feenstra, W. Gsell, L. Reneman,