Altered resting-state effective connectivity of fronto-parietal motor control systems on the primary motor network following stroke

► Stroke is known to cause hemiparesis or weak control of one side of the body. ► Exploratory SEM on healthy controls yielded similar model to motor execution model. ► Altered strength of connection from superior parietal to M1 and SMA after stroke. ► Large individual variance in superior parietal to M1 path strength after stroke.