Article ID Journal Published Year Pages File Type
6033102 NeuroImage 2012 8 Pages PDF
Abstract
►Individuals with Williams syndrome (WS) have significant non-social fears. ►Threatening non-social images elicit amygdala hyperactivity in individuals with WS. ►Amygdala activity is inhibited by the prefrontal cortex (PFC). ►Individuals with WS have lower white matter integrity in PFC-amygdala pathways. ►PFC-amygdala white matter deficits may contribute to amygdala hyperactivity in WS.
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Life Sciences Neuroscience Cognitive Neuroscience
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