Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6033133 | NeuroImage | 2012 | 8 Pages |
Abstract
⺠Investigated the effects of APOE on functional connectivity using resting-state fMRI. ⺠Found differences between APOE genotype groups in several resting-state networks. ⺠Overall, ε4 and ε2 carriers showed similar changes relative to ε3 homozygotes. ⺠Results point to intrinsic, not AD-related, effect of APOE on functional networks. ⺠Role of APOE in neurodevelopment may relate to effects on brain function.
Related Topics
Life Sciences
Neuroscience
Cognitive Neuroscience
Authors
Aaron J. Trachtenberg, Nicola Filippini, Klaus P. Ebmeier, Steve M. Smith, Fredrik Karpe, Clare E. Mackay,