| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6033519 | NeuroImage | 2012 | 10 Pages |
Abstract
⺠[11C]methylphenidate binding to DAT in the mouse brain was quantified in vivo. ⺠Only small differences between in vivo PET and ex vivo AR. ⺠Small test-retest variability and good reliability of PET results. ⺠DVR-1 from Logan graphical analysis agrees well with DVR-1 at true equilibrium. ⺠Dose dependent decrease in displacement experiments and 6-OHDA mouse model of PD.
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![In vivo quantification of dopamine transporters in mice with unilateral 6-OHDA lesions using [11C]methylphenidate and PET](/preview/png/6033519.png "First Page Preview: In vivo quantification of dopamine transporters in mice with unilateral 6-OHDA lesions using [11C]methylphenidate and PET")
Authors
Kristina Fischer, Vesna Sossi, Andreas von Ameln-Mayerhofer, Gerald Reischl, Bernd J. Pichler,