| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6033777 | NeuroImage | 2011 | 7 Pages |
Abstract
⺠Depression is related to hyperactivation of an amygdala-centered (para)limbic network. ⺠Duloxetine attenuates affective processing in same neurocircuitry in healthy humans. ⺠Duloxetine potentiates effective communication between subparts of the network. ⺠This may represent mechanism through which duloxetine normalizes negativity bias in depression.
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Authors
Hein J.F. van Marle, Indira Tendolkar, Maren Urner, Robbert J. Verkes, Guillén Fernández, Guido van Wingen,