| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6034090 | NeuroImage | 2011 | 7 Pages |
Abstract
⺠CNS atrophy in pediatric patients with multiple sclerosis is not yet characterized. ⺠Z-scoring against healthy children is needed to account for age-expected brain size. ⺠TBM identified reduced volumes for thalamus and splenium of corpus callosum. ⺠Splenium atrophy correlated with disease load; optic pathway atrophy, with duration. ⺠Focal inflammatory lesions may be an important cause of tract degeneration.
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Authors
B. Aubert-Broche, V. Fonov, R. Ghassemi, S. Narayanan, D.L. Arnold, B. Banwell, J.G. Sled, D.L. Collins,